The French National Reference Center for Viral Hepatis B, C, and delta (NRC) was created in January 2006, under the direction of Professor Jean-Michel Pawlotsky, following the mandate of the previous NRC, headed by Professor Christian Bréchot, in the context of a reorganization of activities between the coordinating and associated laboratories.
The NRC is housed within the Laboratory of Virology of the Department of "Virology, Hygiene, Bacteriology, Parasitology-Mycology, Transversal unit of Infection Treatment" of the Henri Mondor Medical Center and relies on the skills and expertise of this laboratory, as well as the research group " Physiopathology and Therapeutics of Chronic Viral Hepatitis and related Cancers" (INSERM U955) with which it is affiliated.
The NRC, which performs both medical and scientific activities, has multiple connections, relationships, and collaborations with institutional bodies:
The NRC also cooperates with the public and private sectors involved in surveillance or associated with epidemiology within the framework of their activities (hospitals, clinics, medical biology analysis laboratories, research laboratories, etc.).
Medical personnel assigned to the NRC:
Technical staff assigned to the NRC:
The computer system of the laboratory meets the requirements of a medical biology laboratory that hosts sensitive data, in accordance with article L.1111-8 of the Public Health Code. The computer system consists of a GLIMS laboratory management system and a MEDIWEB results server. These systems meet the standard requirements that guarantee the confidentiality of computerized patient information. The IT infrastructure and related systems are protected by the Information Systems Department (DSI). The DSI ensures: (1) protection of the computer system against computer piracy, especially during remote maintenance, (2) automatic and daily backup of data, and (3) access to patients results according to regulations.
The staff, expertise, equipment of the laboratory of virology, next Generation Sequencing (NGS) platform, and the INSERM U955 research group are available to the NRC for it to carry out its missions.
The following equipment is available to the NRC:
Automated viral serology platform
Automated devices used for the detection and quantification of nucleic acids
Automated devices used for the characterization of viral genome sequences
Materials used for the constitution and conservation of libraries